The semi-automated Exoid device uses new-generation Tunable Resistive Pulse Sensing (TRPS) technology, enabling the measurement of complex nano-particle size, concentration, and charge – with unparalleled precision and accuracy

The 7th Annual “American Society For Exosomes and Microvesicles” meeting held at Pacific Beach, California last week brought together experts and thought leaders in the area of extracellular vesicles (EV) biology.

The “Gold Standard Trial” was carried out by a consortium composed of the following research institutions: Aalborg University Hospital, Denmark;

AN INTERVIEW WITH DR. DE GRACIA LUX - UT SOUTHWESTERN MEDICAL CENTER Tumor Imaging is likely to become much more effective through the use of phase changing (liquid-gas) nanodroplets. Dr. Caroline de Gracia Lux, Assistant Professor in the Department of Radiology at UT Southwestern, explains why in this interesting interview with Izon's Archana Senthikkumar.

Extracellular vesicle researchers are quickly realising the necessity of accurate measurement. Light-based measurement techniques simply provide an estimate and have an unacceptable margin of error. TRPS, on the other hand, can measure particles to within 1nm and is rapidly becoming the Gold Standard in EV research.

Isolating Milk Derived Exosomes

The Role of OMVs in Developing a Vaccine for Actinobacillus Pleuropneumoniae

Continuing advances in the EV field and the discovery of new types of nanosized particles (e.g. exomeres), has lead to researchers wanting more specific and precise EV isolation methods.

Prior to the advent of Size Exclusion Chromatography (SEC) columns, ultra-centrifugation (UC) was regarded as the gold standard for exosome concentration and isolation. UC is time consuming and cannot provide a consistent standardised sample. Based on SEC, qEV columns are the most rapid and effective way to isolate exosomes.

Can EVs forecast cognitive impairment? DR. ANJALI SINGH INTERVIEWS DR. MAJA MUSTAPIC FROM THE LABORATORY OF NEUROSCIENCES (NIA)

The ABC of CBD Written by Anjali Singh

One Small Step for the Production of EV Therapeutics

Izon Science Webinar Series: Single-Particle Zeta Potential Determined by TRPS- Is it More than Just a number?

THE HEART OF THE MATTER

Measuring Nanoparticles with Sub-nm Precision - How Software Works with TRPS.

A new era in exosome and extracellular vesicle (EV) isolation starts this week when the first Automatic Fraction Collectors (AFC) for the qEV SEC column range are shipped to beta customers.

High-Resolution Single Particle Zeta Potential of Biological Nanoparticles An important new paper on single particle charge measurement has been published in Scientific Reports and it’s worth taking a look at it. An extract from the paper is as follows:

Viruses are infectious biological entities usually containing a nucleic acid moiety in a protein coat. They are found abundantly in almost every biota on Earth. However, they are also responsible for causing a variety of diseases, often difficult to cure, due to their ability to integrate and copy themselves within the host cells.

In a candid discourse with Dr. John Ludlow, Executive Director (Regenerative Medicine) at ZenBio, Inc., he talks about the future of customized exosomes as surrogates in regenerative medicine and the roadblocks ahead in the way. Read the article to know more.

Iraj Aalaei is a graduate student from the laboratory of Prof. Dhimiter Bello, University of Massachusetts Lowell, Center for High-rate Nanomanufacturing. The group is using Izon’s instruments in nanotoxicology research with interest in the biological significance of exposure, exposure routes, measurement issues and metrics, the relationship between the physical properties of nanoparticles with health outcomes.

In our first video interview below, Dr Priscila Singorenko from the Dept of Molecular Medicine and Pathology at Auckland University discusses her research on the role of Bacterial Membrane Vesicles in Infection.

Exciting developments in core-shell nanoparticles with tunable shells The potential applications of a new type of core-shell nanoparticle, with tunable titania shells, are covered in this interesting interview with

An interview with of Christoph Metzner, University of Vienna

A robust antibody titer is essential in preventing lung lesions associated with Actinobacillus pleuropneumoniae (App). Dr. Fabio Antenucci from University of Copenhagen explains why in this interesting interview with Archana Senthikkumar from Izon Science.

Review: Exosomes from cultured oral mucosal epithelial sheets promote would healing