Meet Extracellular Vesicle-Associated AAVs: Gene Therapy's Nanoparticle Power Couple
EV-AAVs (sometimes known as exo-AAVs) offer enhanced gene therapy potential over solo-AAVs, thanks to improved transduction and targeted delivery. Obtaining highly purified EV-AAVs is crucial, with size-exclusion chromatography (SEC) proving to be a scalable and effective method for isolation.