Isolate and Characterise: Extracellular Vesicles and Beyond
Streamline extracellular vesicle isolation with the qEV isolation platform. Use tunable resistive pulse sensing (TRPS) to define the physical characteristics of your nanoparticles with unmatched resolution.
Reproducible and Scalable Isolation, Single-Particle Characterisation
Our isolation and measurement techniques bring reproducibility and precision to the extracellular vesicle (EV) field and nanoparticle characterisation. Our qEV Isolation and TRPS measurement technology can be applied to a range of settings involving exosomes, microvesicles, and other extracellular vesicles, as well as viruses, virus-like particles, liposomes and other nanobiologicals.
qEV columns harness principles of size exclusion chromatography to provide an effective approach to EV isolation, and when paired with the Automatic Fraction Collector, streamline and standardise your EV isolation workflow. TRPS is a single-particle measurement technique that utilises the Coulter principle to provide precise, high-resolution measurements on a particle-by-particle basis.
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Size Exclusion Chromatography with the qEV Isolation Platform
The qEV Isolation platform, which consists of qEV columns and the Automatic Fraction Collector, provides a precise, gentle and reproducible approach to EV isolation. By drastically reducing the inefficiencies and error associated with tedious and manual methods, the qEV Isolation platform streamlines separation. qEV Isolation Columns harness principles of size exclusion chromatography to enable the rapid isolation of intact EVs. qEV columns are widely used across the EV field to isolate EVs from plasma, cell culture, and other biological fluids, and have been optimised to conveniently accommodate a wide range of sample loading volumes.
Learn more about qEVSingle-Particle Measurement With Tunable Resistive Pulse Sensing
Izon’s tunable resistive pulse sensing (TRPS) technology provides a true particle-by-particle approach to the physical characterisation of nanoparticles. While traditional light-based techniques are unable to provide precise size-based particle distribution data, TRPS can precisely measure heterogenous samples with a high resolution, allowing you to gain clarity on the physical properties of your sample.
Learn more about TRPSNatalie Turner, PhD Student at Queensland University of Technology
"Izon’s qEV columns offer a simple, effective and reproducible way of purifying EVs directly from biofluids or from EV enriched samples following differential centrifugation. We use the qEV 70 nm legacy (original) columns for all of our EV preps from plasma and milk samples, which undergo downstream processing for mass spectrometry-based proteomics and microRNA sequencing. Our group has produced over 10 publications using these columns and we continue to be satisfied with the results. I would highly recommend incorporating the columns as part of the EV enrichment workflow for any researchers struggling with EV yield and purity."
