Record reliable, number-based measurements of particle concentration
Obtain accurate, number-based measurement of particle concentration to ensure appropriate dosing and drug loading of nanomedicines. Be confident in your quality control and validation processes and evaluations of in vivo particle interactions. Evaluate aggregation, bio interactions of nanoparticles, and the effects of filtering and freeze-thaw of samples.
Particle concentration, total and within specific size bands, needs to be precisely known at all stages of production, storage, and delivery of nanomedicines in order to assess the quality, yield, and extent of aggregation of the sample. As well as being a requirement of validation of complex drug products; the dosage, drug loading, and physicochemical equivalence can only be accurately evaluated when the precise concentration is known. As the only technique to offer number-based data of particle concentration within specified size ranges, which is accurate on a linear scale, Tunable Resistive Pulse Sensing (TRPS) is essential for analysis of heterogenous samples and a crucial aspect of nanomedicine development.