News & Media

When it comes to EV isolation for cancer diagnostics, picking the right methodology could be the difference between succeeding in diagnostics versus failing to achieve sufficient specificity and sensitivity. With qEV columns excelling in purity, your biomarker has a stronger chance at standing out amongst the background noise.

Regulations in nanomedicine are lacking, with no global consensus on definitions and a lack of clarity around which attributes are critical to safety. However, some initiatives and guidelines are in place which may provide indications of what to expect in the future.

From protocols for enriching EVs from complex samples via qEV Gen 2, to understanding the role of bacterial EVs in Alzheimer's disease – and everything in-between. Here are 10 articles which highlight the use of the qEV platform for EV isolation across EV research.

Using qEV columns to determine cargo truly associated with extracellular vesicles and evaluate its biomarker potential in breast cancer: a summary of work by Tkach et al 2022.

Tunable Resistive Pulse Sensing (TRPS) is a versatile analytical technique used to characterise a broad range of nanoparticles used in therapeutic development.

The Exoid is yet to reach its second birthday, yet it has already appeared in a number of impressive research articles. Here are our top 3 extracellular vesicle studies featuring the Exoid to date.

Vogel et al. 2017 describe improvements in nanoparticle zeta potential measurements by Tunable Resistive Pulse Sensing (TRPS).

Has changing your isolation method changed your EV isolate bioactivity? Or perhaps even their cargo or markers? Here’s why.

The Exoid is a highly accurate, highly tunable device which measures single particles in real time for size, concentration and zeta potential. But don’t just take our word for it. We have the data to back it up.

The qEV2 Gen 2 column is the sixth column to join the Gen 2 range; launched on 17th Jan 2023.

100-packs now available for those looking to buy qEVoriginal Gen 2 columns in bulk.

Tunable Resistive Pulse Sensing (TRPS) publication watch: Q4 2022

When is an extracellular vesicle an exosome? Turns out, probably less often than you think. Here we delve into EV subtypes and the (lack of) markers to tell them apart.

The qEV publication watch Q4 2022 wraps up recent research articles using the qEV platform.

Urine is a rich source of EV biomarkers, yet methodology lags behind modern, standardised technology. New studies show size exclusion chromatography as the way forward.

A summary of work by Chiang et al. 2022, feat. qEV and TRPS for studying OMVs from a nosocomial bacterial pathogen.

In conversation with Michiel Pegtel, Principal Investigator at Amsterdam UMC and co-founder of Exbiome, about extracellular vesicle isolation, diagnostics, and EV-miRNA biomarker development.

World Prematurity Day is recognised on November 17 to raise awareness of the challenges of preterm birth. What role might extracellular vesicles play in this space?

Preeclampsia is a major contributor to premature birth. How might extracellular vesicles play a role in pathogenesis, prediction, and treatment?

Breaking it down: why choose qEV columns for extracellular vesicle isolation?

The internal reproductive tract is a potential treasure trove of EVs for fields from assistive reproductive technologies to virology. In this article we discuss it all, from isolation to application.

Synovial fluid is a highly viscous biofluid containing immune cell-derived extracellular vesicles which could prove key to arthritides, but how should you isolate them? And what is already known about them?

Publications featuring Tunable Resistive Pulse Sensing (TRPS) from Q3, 2022.

A comparison of 5 isolation methods for milk extracellular vesicles: a summary of the findings of Morozumi et al. 2021.

The qEV isolation platform continues to contribute to high quality research, as seen in publications from Q3 2022.

Cerebrospinal Fluid presents unique challenges for EV isolation, which has been reflected in a lack of reproducibility in research.

Isolation of brain derived EVs from the circulation and the cerebrospinal fluid is important in the search for biomarkers for neurological diseases. However, the long-held marker, L1CAM, has recently been called into question. Here we discuss the evidence for and against L1CAM as a marker of neuronal EVs.

The methods you use for blood collection and processing will impact on the EVs that end up in your isolated sample. Here we discuss the evidence to help you make the right decisions for your research.

Size exclusion chromatography is a gentle method for isolating pure, intact and functionally active extracellular vesicles. Here we discuss the pros and cons of SEC and other EV isolation techniques.

Interested in using the qEV10 in your research? Here we highlight some of the best examples of research using qEV10 columns published to date.