Chasing L1CAM: A Marker of Brain-Derived Extracellular Vesicles or a Red Herring?
Isolation of brain derived EVs from the circulation and the cerebrospinal fluid is important in the search for biomarkers for neurological diseases. However, the long-held marker, L1CAM, has recently been called into question. Here we discuss the evidence for and against L1CAM as a marker of neuronal EVs.
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