News & Media

Extracellular vesicles (EVs) are making their mark in human medicine - now, they’re showing promise in veterinary care too.

Nanoplastics are tiny plastic particles invisible to the naked eye — but their impact on ecosystems and human health may be anything but small. As research into micro- and nanoplastic contamination increases, tunable resistive pulse sensing (TRPS) is emerging as a powerful method to characterise these elusive pollutants.

Biobanks offer a rich resource for EV research - but are the samples suitable? Explore the practicalities of using biobanked plasma for EV isolation, with a focus on real-world compatibility, sample volume, and storage impact.

Become familiar with SEC+ and the distinct advantages our Gen 2 resin offers over traditional SEC resins, including our discontinued Sepharose-based Legacy columns.

A selection of publications from 2024, demonstrating a range of applications and high-quality performance for Izon’s qEV isolation technology.

A selection of 5 TRPS papers published in 2024.

Early diagnosis of ovarian cancer remains a challenge, but what if the answer lies in the smallest of clues?

Don't let the name mislead you, EVs are not the only nanoparticle qEV columns can purify from a sample. Liposomes and lipid nanoparticles (LNP) can be isolated, too.

EV-AAVs (sometimes known as exo-AAVs) offer enhanced gene therapy potential over solo-AAVs, thanks to improved transduction and targeted delivery. Obtaining highly purified EV-AAVs is crucial, with size-exclusion chromatography (SEC) proving to be a scalable and effective method for isolation.

Unlock the potential of extracellular vesicles for therapeutics with a scalable isolation method that combines tangential flow filtration and qEV columns for optimal efficiency.

What is zeta potential, and how are zeta potential measurements shaping nanomedicine developments?

Catch up on the latest developments in qEV isolation designed to boost scalability in EV isolation across the diverse EV field.

Albumin is a contaminant of extracellular vesicle isolates, right? New research suggests that it may actually be part of the extracellular vesicle corona.

Check out some of the latest research employing qEV columns! A roundup of 10 articles making waves in the EV space.

Let's take a look at the 80-year history of the Coulter counter – the founding principle of TRPS.

Looking for an effective and reliable way to isolate EVs? Consider the AFC – coupled with qEV columns. A combo that is sure to up your EV isolation game.

Everything you need to know about MISEV2023 and how to meet it when publishing your qEV research.

Findings from five recent studies utilising the qEV10 column's benefits for important medical research.

Looking for a versatile tool to add to your research facility’s repertoire? The Exoid has you covered.

Diehl et al., (2023) describe a standardised EV workflow using qEV isolation and TRPS to streamline EV isolation and characterisation protocols.

A wrap-up of publications featuring Tunable Resistive Pulse Sensing technology in Q4 of 2023.

A snapshot of publications built on qEV isolation technology, from the final quarter of 2023.

The qEV100 is used to isolate extracellular vesicles (EVs) from large sample volumes. How does this size exclusion chromatography column stack up against ultracentrifugation?

Introducing the new qEV 20 nm Series, allowing you branch even further into the small end of the size spectrum and isolate more small particles than ever before.

A new Exoid update is here and it is making the measurement of small particles easier and more accurate than ever before.

The International Organization for Standardization has created an ISO standard for Tunable Resistive Pulse Sensing measurement of particle size distribution.

Read about the role of qEV columns in recent stem cell EV discoveries.

A new tier of columns is now available: GMP-ready qEV columns.

If you want the purest EV isolate which qEV column should you pick?

A deep dive into the approaches, considerations and pitfalls of labelling EVs.

What lipid nanoparticle measurement data can you get using the Exoid? Let’s find out.

The future of extracellular vesicle isolation for therapeutics and diagnostics is here.

Struggling with Western blots for extracellular vesicles? This guide will help lead you through the process and its pitfalls.

Regulations in nanomedicine are lacking, with no global consensus on definitions and a lack of clarity around which attributes are critical to safety. However, some initiatives and guidelines are in place which may provide indications of what to expect in the future.

Vogel et al. 2017 describe improvements in nanoparticle zeta potential measurements by Tunable Resistive Pulse Sensing (TRPS).

The qEV2 Gen 2 column is the sixth column to join the Gen 2 range; launched on 17th Jan 2023.

Tunable Resistive Pulse Sensing (TRPS) publication watch: Q4 2022

World Prematurity Day is recognised on November 17 to raise awareness of the challenges of preterm birth. What role might extracellular vesicles play in this space?

Isolation of brain derived EVs from the circulation and the cerebrospinal fluid is important in the search for biomarkers for neurological diseases. However, the long-held marker, L1CAM, has recently been called into question. Here we discuss the evidence for and against L1CAM as a marker of neuronal EVs.

Size exclusion chromatography is a gentle method for isolating pure, intact and functionally active extracellular vesicles. Here we discuss the pros and cons of SEC and other EV isolation techniques.

Isolation, function, and potential future uses of extracellular vesicles derived from milk – a complex and commonly overlooked biofluid.

qEV1: The new SEC column optimised for 1 mL sample loading volumes.

Notes from a conversation with Assistant Professor Stephanie Jung, University Hospital of Bonn (Germany), who separated Hepatitis B and antibodies from EVs to enable functional EV-virology studies.

Sharing the story of France-based researcher Dr Gwennan André-Grégoire, who is working on unravelling the EV-related pathophysiology of glioblastoma multiforme.

On World Hepatitis Day 2021, we explore how researchers are pursuing extracellular vesicles as a way to improve outcomes for people with hepatitis.

A summary of the first ISEV 2021 plenary session by Andrew Hill, La Trobe University. This presentation explored EVs and their role in neurogenerative diseases, with a particular focus on prion diseases.

How is TRPS used to derive EV characteristics? How has a post-processing protocol created new possibilities for zeta potential analysis? Find out in this wrap-up of the ISEV2021 presentation by Dr. Priscila Dauros-Singorenko.

To strengthen the analysis of nanoparticle size, concentration, and charge, Izon Science has released the Exoid – a new-generation Tunable Resistive Pulse Sensing (TRPS) technology.