Extracellular Vesicle News

GMP-Ready qEV Columns Introduced for Enhanced Clinical Translation
A new tier of columns is now available: GMP-ready qEV columns.

Order Legacy Columns Today to Avoid Disappointment
An important notice about the planned phase out of qEV Legacy columns.

Which qEV column delivers the purest EV isolate?
If you want the purest EV isolate which qEV column should you pick?

To Dye or Not to Dye: Labelling Extracellular Vesicles (and Everything Else Unfortunately) with Lipophilic Dyes
A deep dive into the approaches, considerations and pitfalls of labelling EVs.

Introducing the qEV Magnetic Concentration Kit
A new approach to concentrating EVs after qEV isolation, featuring Magnetic Nanotrap® EV Capture Particles.

The Non-Vesicular Wave: Exomeres, Supermeres and Beyond
You know about extracellular vesicles, sure, but what about the new kids on the block? Exomeres and supermeres are here, and they are making a splash in the world of intercellular communication.

Building the Future of EV Isolation: A Q&A With Technology Networks
What does the future of extracellular vesicle isolation have in store, and how is Izon working towards that? Technology Networks speaks to Hans van der Voorn, CEO at Izon Science.

A Tale of Two Techniques: Comparing Size Exclusion Chromatography and Polymer Precipitation for Extracellular Vesicle Isolation
When it comes to yield, purity, expense and time commitment, does size exclusion chromatography or precipitation take the crown for EV isolation?

Are You Testing Protein Fractions in Your Extracellular Vesicle Therapeutics Studies? You Should Be.
How can you be sure that the active ingredient in your extracellular vesicle therapeutic is actually in extracellular vesicles?

Harvesting the Benefits of Plant Extracellular Vesicles
From Arabidopsis thaliana to red cabbage, the field of plant EV (and EV-like nanoparticle) research is a fast-changing world of basic biology and therapeutics. So why is methodology stuck in the past?

Next-Generation EV Separation: Izon Science and Agarose Bead Technologies Collaborate to Enhance Clinical Applications for Extracellular Vesicles
The collaborative agreement between Izon Science and ABT offers exceptional opportunities to develop solutions that aid in advancing EV research into clinical settings.

Maximising Extracellular Vesicle Output: A Small Bioreactor Goes a Long Way
A summary of work by Hisey et al. (2022) who made a huge leap forward in EV production capacity via the use of flask-based bioreactors.

Purity Matters: Why Different EV Isolation Methods Give Different Results
Has changing your isolation method changed your EV isolate bioactivity? Or perhaps even their cargo or markers? Here’s why.

Buy in Bulk: qEVoriginal Gen 2 Columns
100-packs now available for those looking to buy qEVoriginal Gen 2 columns in bulk.

Types of Extracellular Vesicles: From Exosomes to Oncosomes and Everything In Between
When is an extracellular vesicle an exosome? Turns out, probably less often than you think. Here we delve into EV subtypes and the (lack of) markers to tell them apart.

Exploring EVs from a Hospital-Derived Bacterial Pathogen With the Exoid and qEV10
A summary of work by Chiang et al. 2022, feat. qEV and TRPS for studying OMVs from a nosocomial bacterial pathogen.

Extracellular Vesicles and Preeclampsia: From Pathogenesis to Diagnostics and Therapeutics
Preeclampsia is a major contributor to premature birth. How might extracellular vesicles play a role in pathogenesis, prediction, and treatment?

Potential Applications of Reproductive Extracellular Vesicles: From Human Fertility to Agriculture and Beyond
The internal reproductive tract is a potential treasure trove of EVs for fields from assistive reproductive technologies to virology. In this article we discuss it all, from isolation to application.

Synovial Fluid Extracellular Vesicles: Footsoldiers of Inflammation?
Synovial fluid is a highly viscous biofluid containing immune cell-derived extracellular vesicles which could prove key to arthritides, but how should you isolate them? And what is already known about them?

Compare 5 Approaches to Milk EV Isolation: Findings From Morozumi et al 2021
A comparison of 5 isolation methods for milk extracellular vesicles: a summary of the findings of Morozumi et al. 2021.

From Astrocytoma to Preeclampsia: 4 Recent TRPS Articles Spanning the EV Field
Publications featuring Tunable Resistive Pulse Sensing (TRPS) from Q3, 2022.

Extracellular Vesicles From Cerebrospinal Fluid: Current State of the Research
Cerebrospinal Fluid presents unique challenges for EV isolation, which has been reflected in a lack of reproducibility in research.

Plasma Extracellular Vesicles: Does Anticoagulant Type Matter?
The methods you use for blood collection and processing will impact on the EVs that end up in your isolated sample. Here we discuss the evidence to help you make the right decisions for your research.

Extracellular Vesicle Isolation: Why Size Exclusion Chromatography Is on the Rise
Size exclusion chromatography is a gentle method for isolating pure, intact and functionally active extracellular vesicles. Here we discuss the pros and cons of SEC and other EV isolation techniques.

Milk Extracellular Vesicles: Isolation, Function and Future Uses
Isolation, function, and potential future uses of extracellular vesicles derived from milk – a complex and commonly overlooked biofluid.

Extracellular Vesicles and MicroRNA: Definitions, Discovery, Clinical Potential and Open Questions
Reflecting on the discovery, open questions and potential applications of microRNA, and microRNA derived from extracellular vesicles.

7 Considerations for Storing Samples Prior to Extracellular Vesicle Isolation
When it comes to EV storage, there are many variables to consider. Here, we share 7 factors to consider between the time of collection until samples are processed for EV isolation.

World Cancer Day 2022: Addressing Questions in EV-based Biomarker Development
On World Cancer Day 2022, we look to progress and challenges in areas critical to the development of extracellular vesicle-based biomarkers for early cancer detection.

Tasmanian Devils Endangered: Uncovering EV Biomarkers to Aid Conservation Strategies
The Tasmanian devil species is threatened by transmissible facial tumours. Do extracellular vesicles hold the key to better conservation strategies?

To Cut Through the Noise in Extracellular Vesicle Analysis, Reproducible Isolation is Essential
Why the signal-to-noise ratio is important for EV-based diagnostics.