The Exoid: Versatile Measurement for Complex Samples
For researchers who need flexible, high-resolution measurement of complex nanoparticle samples.
Based on the established TRPS platform, the Exoid measures particle size, concentration, and zeta potential on a particle-by-particle basis. Its tunable nanopores support a broad range of complex samples, delivering accurate, proven single-particle data you can trust.
Start a conversation about the ExoidMeasure Nanoparticles with Single Particle Resolution
Using Tunable Resistive Pulse Sensing (TRPS), the Exoid measures nanoparticles one-by-one as they pass through a tunable nanopore, allowing you to obtain measurements of particle size and concentration, or particle size and zeta potential, on a single-particle basis. Unlike ensemble techniques, where larger particles can skew size measurements, the Exoid provides insightful, high-resolution measurements that allow you to detect important differences in particle size distribution.
Tunable nanopore technology supports a broad size range and diverse particle types, giving researchers maximum flexibility.
Thousands of peer-reviewed publications and years of proven performance across academic and applied research.
Precise, particle-by-particle measurement of size, concentration, and zeta potential, trusted across thousands of studies.
A Proven, Standardised Platform
Tunable Resistive Pulse Sensing (TRPS) measurements have in-built requirements which ensure a standardised approach to measurement:
Traceable calibration
Measurements are calibrated using Izon standards characterised against NIST particles, ensuring reproducible and comparable results.
Real-time system feedback
Live monitoring of current and noise helps maintain stable, high-quality measurements.
Buffer control checks
Running a particle-free buffer confirms that detected events represent true particles in the sample.
EV-ready workflow
Pair with qEV isolation to support consistent, standardised EV characterisation.
Characterise Your Samples Confidently With the Exoid
The Exoid enables detailed, single-particle analysis across a broad range of nanoparticle types. Measure particle size and concentration from 40 nm to 11 µm, and size and zeta potential from 40 nm to 2,000 nm, using interchangeable nanopores to match your sample.
Its wide dynamic range and tunable measurement conditions make it well suited to complex or heterogeneous samples, including extracellular vesicles, lipid nanoparticles, virus-like particles, and other biological or synthetic nanoparticles.
For researchers who require flexibility and depth of insight across diverse particle systems, the Exoid remains a trusted and versatile platform.
What Can You Expect From the Exoid?
Over the years, TRPS instruments have evolved significantly, improving usability and workflow compared with earlier generations.
That said, the Exoid remains a hands-on platform. Users adjust measurement conditions and occasionally troubleshoot to maintain optimal performance, particularly when working with complex samples.
With training and experience, this level of control becomes a strength, enabling detailed analysis across a wide range of particle types.
Izon provides training and ongoing support to help users get the most from the system.
Skill Required for Insightful, Reliable Nanoparticle Measurements
As particle size decreases, measurement becomes more technically demanding. Smaller particles require tighter control of conditions, careful calibration, and greater user skill to obtain reliable data.
The Exoid is designed to deliver precise, repeatable single-particle measurements across a wide size range, including challenging sub-100 nm particles. Achieving optimal results requires good sample preparation and active user oversight.
For experienced users who value flexibility and control, this involvement enables robust, defensible data, particularly at the smallest sizes.
Specifications of the Exoid TRPS Measurement System
Analysis range
40 nm to 11 µm
Compatible electrolyte solutions
Include PBS, HEPES, MES and KCI
Footprint
300 x 300 mm
Concentration range
1E5 to 1E11 particles/mL
(size-dependent)
Weight
10.8 kg
Height
250 mm
Pricing
There are a number of ways you can incorporate the accuracy and precision of TRPS in your research. You can buy the Exoid outright for $47,500 USD, or get in touch with our team to discuss a lease agreement. Alternatively, we also offer sample measurement services for our EU and US customers. All prices listed below are in USD.
$47.5K
$4.5K / month
$350 / sample
