4 Reasons Why You Should Use qEV SEC Columns for Your Exosome Isolation

qEV elution profile and concentration measurement
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Izon’s qEV columns harness size exclusion chromatography (SEC) to provide a rapid and effective method for the isolation of exosomes and other extracellular vesicles.

Prior to the advent of SEC, ultra-centrifugation (UC) was regarded as the gold standard for the concentration and isolation of exosomes and other extracellular vesicles (EVs). However, UC is highly time-consuming and difficult to standardise.

Here are 4 reasons why you should be using qEV SEC columns for your exosome isolation:

  1. qEV columns preserve the physical function and biological integrity of your exosomes and provide the purest isolation from complex biological samples including serum, plasma, saliva, CSF, urine and cell cultures.
  2. They are simple to use and very fast. No expensive equipment is required, isolation takes 15 minutes and the cost per sample is very low.
  3. qEV, particularly when combined with TRPS measurement, offers a well-standardised protocol for exosome isolation and measurement, with the lowest CV of any system available. Standardisation and repeatability are critical for success in diagnostics applications and in EV based therapeutics.
  4. Recovery efficiency is very high, up to 93%.


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Written by alex@kholab.co, last updated 14/9/21 Tag ID replacement script. Used to replace all text divs with the attribute 'tag-replace', with value 'applications', 'products', or 'tags' with their corresponding display names. This script only needs to be included once for every page which requires these translations.