qNano

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Izon's qNano utilizes a new non-optical detection principle to enable the size, concentration, dynamics and charge of a wide range of particle types to be measured with unsurpassed accuracy.

Particle-by-particle characterization can occur, covering a size range beyond that of flow cytometry and conventional coulter counters - and with more accuracy than light-based measurement. 

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Key features of the qNano include:

Accurate Particle Size & Sample Polydispersity - Resistive Pulse Sensing combined with Size Tunable Nanopores enables accurate particle-by-particle measurement with representative information on the size and polydispersity of mixtures, without skewing of data as occurs with intensity-weighted biased approaches such as dynamic light scattering (DLS).

Quick, Precise Concentration Determination - Resistive pulse sensing allows particles to be counted with high precision, thus enabling rapid determination of the number of particles per mL of sample. A large concentration range is covered, extending from 10^5 to 10^12 particles per mL.

Real-Time Monitoring & Confirmation of Particle Interactions. Particle-by-particle measurement builds up population-level data in real time allowing the dynamics of particle-particle, particle-biomolecule, functionalization and aggregation interactions to be analysed.

Wide Range of Particle Types - Viruses - Adenovirus, Lentivirus, Baculovirus, HIV, H1N1, H7N3, CMV, Dengue, Flu viruses, Phage, EV7 Bacteria & Cells, E.Coli, Plankton, Shewanella, Bacilli, Cocci, yeast .. Virus-like-Particles, Blood Platelets, Liposomes, Exosomes, Protein Bioconjugates, Vesicles .. Bio-fragments, micelles, lipids, Cubosomes... Polymeric, PLGA, Hydrogels, Emulsions, Polystyrene, PMMA Magnetic, Titania, Silica, Pt, Gold...

Physiological conditions. Small sample size - Analysis involves pipetting 40μl of sample into the sample chamber of the qNano. There is no need for pre-treatment of samples meaning biologically relevant conditions can be studied, and the level of aggregation can be determined for instance.

Compact. Portable. Rapid - qNano is compact (~12.5cm base, 22cm tall) and portable, and offers rapid analysis (analysis of thousands of particles usually takes 10-15 minutes)

Cost Effective - qNano offers applications not previously available to researchers at a fraction of the cost of the incumbent technologies.

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Key Applications:


  • Drug Delivery Research Exosome & Microparticle Analysis Virus Analysis & Quantitation
    Liposomes, Nanobubbles, Polymers, "Smart" Drug Delivery Particles Exosomes & Microparticles, Platelets, Whole Blood Cells Viral Vectors, Viral Vaccines, Virus-Like-Particles
    Drug Delivery Research (E.g. Liposomes, Polymers, "Smart" Particles)
  • Biomedical Diagnostics Research & Development (E.g. Dye-doped Nanoparticles, Functionalized Nanoparticles for Immunodetection)
  • Industrial Research Applications (E.g. Paints & Emulsions, Food & Beverage, Metallic & Magnetic Particles)


qNano Package

The qNano is sold as a full system ready for use including the base instrument, variable pressure module (VPM), fluid cell and a starter kit of nanopores, buffer solution and standard particle sets.

For further information and pricing or to order a qNano system please see  Orders and Sales.

qNano