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Tuning Particle Velocity and Measurement Sensitivity by Changing Pore Sensor Dimensions

Darby Kozak, Will Anderson, Matt Trau
Chemistry Letters. Vol. 41 (2012) No. 10 P 1134-1136

Tuning the size of an elastic pore sensor enables the control of both the measurement sensitivity and particle velocity through the pore. Increasing the pore size by stretching the pore membrane reduced the magnitude of the resistive pulse signal generated by 330 nm polystyrene particles by 24% while simultaneously increasing their velocity through the pore, as shown by the 68% shorter pulse durations. These effects are due to the reduced excluded particle volume and increased fluid velocity through the larger pore, respectively.

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