Components & Consumables

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Nanopores

Izon’s nanopores make our SIOS technology platform tuneable and dynamic.

The nanopores are manufactured in a thermoplastic polyurethane cruciform using a proprietary technique. When fitted to the qNano or qViro instruments, the cruciform can be stretched evenly along the x and y axes to effect nanometre scale adjustments to the nanopore.

Nanopores are robust and easy to handle. They can be used repeatedly, cleaned and re-used, or simply disposed of after one use depending upon the nature of work being undertaken.  The lifetime of each nanopore depends upon the nature of use. Repeated operation to maximum stretch and relaxation will cause the nanopore to wear more quickly.

Nanopores can be made according to the particle size range required. Each one is individually tested to ensure that its optimal performance range is characterised before it is supplied to the customer.

Three nanopores are supplied with each qViro and qNano instrument system. Additional, individually tested and characterised nanopores are available in packs of ten for purchase from Izon. For further information or to order additional nanopores please see Orders and Sales.

Nanopores

Fluid Cells

Izon’s fluid cells are designed for ease of fitting to instruments and safe handling of fluids.

Each fluid cell is comprised of two sections, the top and bottom sections of the fluid cell being connected together after the nanopore cruciform has been positioned between the two halves. The minimum volume of sample fluid required is 40 microlitres.

Direct access points to the fluid in the upper and lower fluid cell compartments allows for easy and safe handling of samples.

An electrical connection is made to the bottom of the fluid cell via a shielded SMA connector. Silver chloride electrodes are fitted into the fluid cell.  The fluid cell is designed with shielding to minimize electrical noise.

Each qNano and qViro instrument is supplied with one fluid cell. Additional fluid cells can be purchased from Izon.

For further information or to order additional fluid cells please see Orders and Sales.

Fluid Cells

Variable Pressure Module

The Variable Pressure Module (VPM), Izon’s next generation development in nano-sized particle analysis technology, extends the existing detection, measurement and research capabilities  of the qNano and qViro instruments.

 

Platform system for advanced research 

The VPM provides pressure and vacuum control of sample flow, complementing the electrophoretic operation of the qNano and qViro instruments. This provides the ability to conduct novel research into nanopores and nano/microfluidic systems.

Uncharged and charged particle detection

The VPM extends the measurement capability of Izon’s qNano and qViro  instruments to allow charged and uncharged particles to be detected by the system

Extended sample electrolyte compatibility

Pressure driven particle flow extends the range of particle-electrolyte combinations compatible with the system.

Next generation concentration analysis
Used in conjunction with Izon’s qNano or qViro instrument, 
the VPM provides an advanced and effective approach 
for measurement of nano-sized particle concentrations in both 
biological and synthetic particle samples.
extended concentration range sensitivity
The additional sample flow generated by the VPM adds two orders of mangitude to the lower detection limit of the qNano 
and qViro instruments. Sample concentrations down to around 10
5
 particles per mL may be measured
1
.
Particle charge and mobility analysis
By finely controlling and balancing electrophoretic and pressure forces exerted on the particle, detailed mobility and charge 
information can be extracted in a wide range of electrolyte environments

Next generation concentration analysis

Used in conjunction with Izon’s qNano or qViro instrument,  the VPM provides an advanced and effective approach for measurement of nano-sized particle concentrations in both  biological and synthetic particle samples. 

Extended concentration range sensitivity

The additional sample flow generated by the VPM adds two orders of magnitude to the lower detection limit of the qNano and qViro instruments. Sample concentrations down to around 10^5 particles per mL may be measured.

Particle charge and mobility analysis

By finely controlling and balancing electrophoretic and pressure forces exerted on the particle, detailed mobility and charge information can be extracted in a wide range of electrolyte environments.

Variable Pressure Module