Smart Drug Delivery at JHU Cancer Symposium
Aaron Colby, a PhD student of Prof. Mark Grinstaff, who featured in our March newsletter, presented a poster titled “pH-Responsive, Expansile Nanoparticles for Drug Delivery” at the Annual Nanobio symposium held at John Hopkins University on Friday 13 May.
Aaron is working with a group at Boston University's Center for Nanoscience and Nanobiotechnology, led by Prof. Mark Grinstaff, who are developing ‘expansile’ particles and hydrophilic triggers for targeted drug delivery. Specifically, new particle compositions are being developed that are pH responsive, which swell and release their contents once inside cancer cells.
The qNano platform has enabled accurate measurement of expansile nanoparticles, allowing detection of very subtle changes in various parameters (size, surface charge and concentration) before during and after exposure to different experimental conditions. The work highlights how qNano is being used by research groups as a highly accurate tool for characterization of smart drug delivery particles, which could not be obtained by other measurement methods.
The fifth annual nano-bio symposium, organized by The Johns Hopkins Institute for NanoBioTechnology, was held on May 12-13. The symposium, themed “Cancer Nanotechnology” featured talks from a slate of faculty experts in nanoscience, oncology, engineering and medicine.